Medical Education has been known conventionally taught and learnt in an inductive way and has been considered as a difficult one to both impart and imbibe. Information and Communication Technology (ICT), mostly as e-learning, has made the process of education much easier to comprehend. However, the application of medical informatics tools to medical education has been quite delayed and inadequate, especially in India. The paper discusses the pros and cons of e-learning and tries to suggest step-by-step primer for setting up effective e-learning courses for medical education.